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Health & Disease

The curious case of low-protein diets

In the lab, animals live longer on less of the stuff. How could this be, and what does it mean for human aging?

Progress fighting pancreatic cancer — one of the deadliest malignancies

Better outcomes may come from new drugs, strategies to rev up the immune system and learning to identify the disease sooner in its course

Journey to the egg: How sperm navigate the path to fertilization

COMIC: Male cells must survive twisty passages, strong currents and immune attacks; millions enter, but only one can finish

How rogue jumping genes can spur Alzheimer’s, ALS

Our genomes are peppered with DNA segments called retrotransposons that can move from place to place. When unleashed, some can kill nerves and promote inflammation — a discovery that may inspire treatments for neurodegeneration.

Worm-inspired treatments inch toward the clinic

Infection by certain wrigglers may reduce inflammation and fight obesity and diabetes. Scientists are at work to turn the findings into therapies.

Everything you need to know about bird flu

How dangerous is it? Where did it come from? H5N1 influenza’s origins stretch back to the 1990s, and key events paved the way for the outbreak we’re seeing today.

How cancer cells travel to new tissues and take hold

Understanding these astonishing migrations through the human body, known as metastases, could suggest novel treatments

Pig organs in people: The future of cross-species transplants

Can genetically modified animals help ease the shortage of organs? After years of research into xenotransplantation, the field is at a turning point — yet risks and ethical issues remain.

We are all genetic mosaics

Picture your body: It’s a collection of cells carrying thousands of DNA errors accrued over a lifetime — many harmless, some bad, and at least a few that may be good for you.

Studies of migraine’s many triggers offer paths to new therapies

One class of drugs has already found success in treating the painful, disorienting and common attacks. Excitement is building about a slew of additional drug targets.

Why a diabetes drug fell short of anticancer hopes

Population and animal studies suggested it could treat cancer, but the clinical trials were a bust. Here’s what happened and what potential may remain.

Your cells are dying. All the time.

Some go gently into the night. Others die less prettily in freak accidents or deadly invasions, or after a showy display.

The phageome: A hidden kingdom within your gut

Human innards are teeming with viruses that infect bacteria. What are they up to?

All about cholesterol

The latest science on how blood levels of HDL, LDL and more relate to cardiovascular health

CRISPR gene editing: Moving closer to home

With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot going on in the genome editing field. Here’s our primer.

Genes and heart disease: Finally making the link

Polygenic risk scores — a patient’s chance, based on tiny DNA variants, of developing cardiovascular disease, breast cancer and more — are coming to clinics. But there are kinks to iron out and accuracy remains an issue.

Scientists scrutinize happiness research

From meditation to smiling, researchers take a second look at studies claiming to reveal what makes us happy

Salt taste is surprisingly mysterious

Too much sodium is bad, but so is too little — no wonder the body has two sensing mechanisms

The neurons that make us feel hangry

Neuroscientists think a cluster of cells in the brain that stimulate appetite could be a target for eating disorder therapies

Amyloidosis: Beyond Alzheimer’s and Parkinson’s

Amyloid plaque can build up in body organs other than the brain. The resulting diseases — AL amyloidosis, ATTR amyloidosis and more — cause much suffering.

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