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Explained

Artwork showing neurons along with the tangles of tau protein and clumps of amyloid-beta plaques that are typically found in the brains of patients with Alzheimer’s disease. Investigating when and how these proteins form might lead to new therapies.
Health & Disease

Watching Alzheimer’s in action

A look inside the brains of engineered mice suggests therapies might need to target two key proteins — tau and amyloid-beta — at the same time

Photograph of two elderly men sitting outdoors. They are enjoying a good joke or tale. The man on the left has his arms around the shoulders of his friend. He ls laughing. The man on the right has his arms out in front, slightly raised, as if he is relating a story. He is grinning.
The Mind

Emotions get better with age

As people grow older, they gain greater control of their feelings. How do they do that — and can they teach young whippersnappers a thing or two?

Photo of an old rhesus macaque putting something on her mouth. She sits on what looks like a beach or bare ground. Vegetation is behind her.
The Mind

It’s not just us: Other animals change their social habits in old age

In patterns that may sound familiar, long-term studies reveal what elderly deer, sheep and macaques are up to in their twilight years

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