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Health & Disease

The silent majority: RNAs that don’t make proteins

Once considered cellular junk, non-coding RNAs are emerging as key players in everything from brain development to cancer — with much still to be discovered

Sweet! The cell’s sugary coating comes into view

Built from thickets of glucose, galactose, mannose and more, the glycome plays key roles in cell communication, immunity and the blood-brain barrier

Beating back the Aedes aegypti mosquito

Scientists are taking a multipronged approach to tackle this dangerous carrier of dengue, yellow fever and other noxious viruses

Top science stories of 2025

In a year of funding chaos, ongoing climate change and pollution perils, we also saw the most powerful telescope yet, personalized gene therapy, and the next-best-thing to an HIV vaccine — not to mention a brand-new color

Progress fighting pancreatic cancer — one of the deadliest malignancies

Better outcomes may come from new drugs, strategies to rev up the immune system and learning to identify the disease sooner in its course

Achieving lasting remission for HIV

People infected with HIV must take antiretroviral drugs for life. But promising trials using engineered antibodies suggest that ‘functional cures’ may be in reach.

Postpartum depression: Better remedies, and now a predictive blood test

Scientists are learning more about this leading complication of childbirth. Treatments are improving and doctors can test for biological markers that flag heightened risk.

Tracking down the hidden pollutants that make wildlife sick

A new technique for detecting unknown and unlooked-for chemicals is revealing dozens of contaminants in alligators, sea lions and condors

The clock is ticking: How epigenetics could help save wildlife from collapse

In polar bears, dolphins, baboons and more, molecular signatures of aging are changing how conservationists assess population health, resilience and risk

Mighty mitochondria: Cell powerhouses harnessed for healing

Infusion of the tiny, sausage-shaped structures helps to rejuvenate tissues deprived of blood. Researchers hope the technique can treat a variety of damaged organs.

Worm-inspired treatments inch toward the clinic

Infection by certain wrigglers may reduce inflammation and fight obesity and diabetes. Scientists are at work to turn the findings into therapies.

Shared mobility: Making travel easier for all

Carshares, bikeshares and the like are a positive for the environment, though access to them isn’t equal. What can be done to give everyone more transportation options?

Pig organs in people: The future of cross-species transplants

Can genetically modified animals help ease the shortage of organs? After years of research into xenotransplantation, the field is at a turning point — yet risks and ethical issues remain.

Top science stories of 2024

This record-setting year for heat saw stunning auroras, a map of a brain, a Dengue epidemic, the first look at rocks from the far side of the Moon, an AI energy scramble and more

The great green building makeover

Getting our homes and workplaces to be energy efficient has major benefits — but not when it is done one window at a time. Here’s why deep retrofits and biomaterials are key to more sustainable living.

The Cybathlon: Bionic athletes compete for the gold — and push assistive technologies forward

In the international competition, people with physical disabilities put state-of-the-art devices to the test as they race to complete the tasks of everyday life

Targeting the racial disparity in kidney disease

Some people of West African descent face a higher risk of renal failure. New drugs based on gene research may help right the ship — if they can reach everyone who needs them.

What if a virus could reverse antibiotic resistance?

In promising experiments, phage therapy forces bacteria into a no-win dilemma that lowers their defenses against drugs they’d evolved to withstand

Radioactive drugs strike cancer with precision

The tumor-seeking radiopharmaceuticals are charting a new course in oncology, with promise for targeted treatments with fewer side effects

The untapped potential of stem cells in menstrual blood

Long overlooked, menstrual stem cells could have important medical applications, including diagnosing endometriosis

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