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The Mind

The silent majority: RNAs that don’t make proteins

Once considered cellular junk, non-coding RNAs are emerging as key players in everything from brain development to cancer — with much still to be discovered

Sweet! The cell’s sugary coating comes into view

Built from thickets of glucose, galactose, mannose and more, the glycome plays key roles in cell communication, immunity and the blood-brain barrier

A light in the dark: Finding the good in the natural world

OPINION: Is it absurd to think that science can inform our values? Not at all, says writer KC Cole.

What is wisdom, and can it be taught?

Scientists are trying to name the qualities that make someone wise and figure out how to cultivate them

Looking for an ADHD coach? Choose carefully

As diagnoses surge, so does an unregulated coaching industry

The curious life of a clever slime mold

In its quest to feed, avoid nasty substances and just generally live its life, the brainless, one-celled Physarum polycephalum performs some impressive tricks of learning and memory

Recreating the smells of history

Using chemistry, archival records and AI, scientists are reviving the aromas of old libraries, mummies and battlefields

Postpartum depression: Better remedies, and now a predictive blood test

Scientists are learning more about this leading complication of childbirth. Treatments are improving and doctors can test for biological markers that flag heightened risk.

Property crime and violent crime have different solutions — here’s why

Addressing poverty helps to curb thefts and burglaries, but offenses like assaults and shootings need more innovative approaches

Corruption: When norms upstage the law

People with good motives may engage in bribery and worse depending on what society expects of them. A political scientist explains.

Can a shift in strategy reduce intimate partner violence?

New research, innovative programs and emboldened advocates are challenging decades-old conventions about how to respond to domestic abuse

Unsafe at home: The misery of intimate partner violence

Public health researchers explain the levers that can reduce — or worsen — this global blight. A bright spot: There are more data than ever on strategies that can help.

See something, say something? The science of speaking out

From tattling to whistleblowing, a sociologist explores what drives people to tell on one another

How rogue jumping genes can spur Alzheimer’s, ALS

Our genomes are peppered with DNA segments called retrotransposons that can move from place to place. When unleashed, some can kill nerves and promote inflammation — a discovery that may inspire treatments for neurodegeneration.

How stress shapes cancer’s course

Studies show psychological strain can accelerate tumors — could beta blockers slow them down?

It began with a rabbit: Unraveling the mystery of memory

Half a century after the discovery of long-term potentiation, we’re still learning how the brain remembers

Huh? The valuable role of interjections

Utterances like um, wow and mm-hmm aren’t garbage — they keep conversations flowing

Speech interjections aren’t throwaway lines

PODCAST: Turns out, the best listener isn't quiet, as our host learns in a chat with two linguists. All those ums, ohs and mm-hmms have unexpected value.

Meet the capuchin monkey: Curious, creative and vengeful

UCLA’s Susan Perry has devoted decades to studying the fast-motion life of these New World primates and learning how the young acquire the skills they need to thrive

Quiet couples: Alone time together

The right kind of silence can be golden, revitalizing and strengthening a relationship

We are all genetic mosaics

Picture your body: It’s a collection of cells carrying thousands of DNA errors accrued over a lifetime — many harmless, some bad, and at least a few that may be good for you.

Top science stories of 2024

This record-setting year for heat saw stunning auroras, a map of a brain, a Dengue epidemic, the first look at rocks from the far side of the Moon, an AI energy scramble and more

Making friends with your past and future selves

It’s what psychologists call self-continuity, and can improve your health and well-being

The ones who need little sleep

Short sleepers cruise by on four to six hours a night and don’t seem to suffer ill effects. Turns out they’re genetically built to require less sleep than the rest of us.

Severe irritability in children and teens: A new understanding

Kids with disruptive mood dysregulation disorder have explosive outbursts well past toddler age. Scientists are trying to work out the causes and what treatments help.

Night of the zombie insects

A parasitic fungus takes over the brains of flies and controls them for its own sinister ends. Here’s the science behind the horror.

How a child becomes bilingual — and what can be done to help them get there

Kids from immigrant backgrounds in the US often struggle to develop fluency in two languages. Many factors — parental misconceptions, the lack of support in schools and social attitudes — play a role.

The Cybathlon: Bionic athletes compete for the gold — and push assistive technologies forward

In the international competition, people with physical disabilities put state-of-the-art devices to the test as they race to complete the tasks of everyday life

Studies of migraine’s many triggers offer paths to new therapies

One class of drugs has already found success in treating the painful, disorienting and common attacks. Excitement is building about a slew of additional drug targets.

What’s that smell — and how’d you know?

It’s clear that genes, receptors and neurons all play a role in detecting odors. But much of how we make sense of what we sniff remains mysterious. A neuroscientist explains.

The tussle over cigarette warning labels, and the hazy future of vaping

Regulatory hurdles, industry objections and legal fights have gone on for decades over traditional tobacco. What’s in store for the next generation of smoking?

Divided we stand: The rise of political animosity

Scientists peered into the partisan abyss. Here’s what they found.

Are you a workaholic? Here’s how to spot the signs

In a major shift, psychologists now view an out-of-control compulsion to work as an addiction with its own set of risk factors and consequences

It’s not just us: Other animals change their social habits in old age

In patterns that may sound familiar, long-term studies reveal what elderly deer, sheep and macaques are up to in their twilight years

Abracadabra! How magic can help us understand animal minds

By performing tricks for birds, monkeys and other creatures, researchers hope to learn how they perceive and think about their world

To pee or not to pee? That is a question for the bladder — and the brain

How do we sense the need to urinate? The basic urge is surprisingly complex and can go awry as we age.

Time for half-year resolutions?

If your good intentions from a few months ago haven’t led to much, take note. A psychologist tells us what we can learn from studies on willpower.

Fit for a dog? The latest science on CBD for pets

Though studies are still mixed, and products often inconsistent, many scientists have hope that cannabidiol can help canines and other furry patients suffering from arthritis, allergies and anxiety

When are parents responsible for their kids’ behavior?

A researcher weighs in on who’s accountable, when and why, in the eyes of the law — and whether the measures work as intended

What’s next in the Ozempic era?

Diabetes, weight loss and now heart health: A new family of drugs is changing the way scientists are thinking about obesity — and more uses are on the horizon

Why do some people always get lost?

Research suggests that experience may matter more than innate ability when it comes to a sense of direction

Psychedelic drugs and the law: What’s next?

The push to legalize magic mushrooms, MDMA, LSD and other hallucinogens is likely to heighten tensions between state and federal law, drug law expert Robert Mikos says

Soda taxes can’t reverse the obesity epidemic

OPINION: They might be able to help, but only if well-designed and in combination with other policies

Lessons from sports psychology research

Scientists are probing the head games that influence athletic performance, from coaching to coping with pressure

Indigenous languages are founts of environmental knowledge

Peoples who live close to nature have a rich lore of plants, animals and landscapes embedded in their mother tongues — which may hold vital clues to protecting biodiversity

How gut bacteria connect to Parkinson’s disease

Growing evidence suggests a link between the debilitating neurological illness and the microbes that live in our intestines. The vagus nerve may be a pathway.

The growing link between microbes, mood and mental health

New research suggests that to maintain a healthy brain, we should tend our gut microbiome. The best way to do that right now is not through pills and supplements, but better food.

Scientists scrutinize happiness research

From meditation to smiling, researchers take a second look at studies claiming to reveal what makes us happy

Top science stories of 2023

Twelve standout news events and trends in a tumultuous year

Neanderthals: More knowable now than ever

They have held our fascination ever since we first identified their remains. Today, thanks to new artifacts and technologies, findings about our closest relatives are coming thick and fast.

A magnetic therapy for depression gains precision

Approved over a decade ago, transcranial magnetic stimulation (TMS) is moderately effective. Tailoring the treatment to individual brains may improve results.

Do spiders dream? What about cuttlefish? Bearded dragons?

Researchers are finding signs of multiple phases of sleep all over the animal kingdom. The ‘active’ sleep phases look very much like REM.

Charles Henry Turner’s insights into animal behavior were a century ahead of their time

Researchers are rediscovering the forgotten legacy of a pioneering Black scientist who conducted trailblazing research on the cognitive traits of bees, spiders and more

The psychopathic path to success

Psychopathic tendencies may be present to some extent in all of us. New research is reframing this often sensationalized and maligned set of traits and finding some positive twists.

Medications for opioid use disorder — MOUD — and adolescents

Treatment with drugs such as buprenorphine, methadone and naltrexone is deemed the gold standard for youth with opioid addictions. Why isn’t it used more often?

How the placebo effect went mainstream

PODCAST: Sloppy by today’s standards, and maybe even back when it was published in 1955, Henry Beecher’s paper paved the way for sounder drug trials and pushed scientists to better understand how we process pain (Season 3, Episode 3)

Better therapy for Asian Americans

Most of today’s psychotherapies are grounded in Western values. Researchers hope that tailoring treatments to patients’ cultural backgrounds will improve mental health outcomes.

The neurons that make us feel hangry

Neuroscientists think a cluster of cells in the brain that stimulate appetite could be a target for eating disorder therapies

Reading the mind with machines

Researchers are developing brain-computer interfaces that would enable communication for people with locked-in syndrome and other conditions that render them unable to speak

Teens can have excellent executive function — just not all the time

Adolescents’ brains are highly capable, if inconsistent, during this critical age of exploration and development. They are also acutely tuned into rewards.

Hope for haploinsufficiency diseases

Genetic conditions like Dravet syndrome, which causes severe childhood epilepsy, are hard to tackle with traditional gene therapy. New approaches in the works include using antisense therapy to boost mRNA splicing.

Zooming in on the brains of babies

New tools are helping neuroscientists investigate why early life is such a crucial time for neural development

Animal personalities can trip up science, but there’s a solution

Individual behavior patterns may skew studies. A new approach called ‘STRANGE’ could help, by taking into account the habits, tendencies and life experiences of the creatures under scrutiny.

The baby brain: Learning in leaps and bounds

VIDEO: Learn how the baby brain changes from gestation to toddlerhood, and what parents, teachers and policymakers can do to ensure kids are set up for success

The teen brain: Mysteries and misconceptions

VIDEO: Join a conversation about the teenage brain’s strengths and vulnerabilities, how adults can support teenagers with mental health issues, and how teens can help one another

The mature mind: Aging resiliently

VIDEO: Connect with brain health experts about the best ways to cultivate resilience as we age, and how to support loved ones with memory loss and dementia

What makes for a ‘great’ sex life?

Research into intimacy upends many popular notions about sexual fulfillment. One hint: It’s more about connection than technique.

Scientific highs and lows of cannabinoids

Hundreds of these cannabis-related chemicals now exist, both natural and synthetic, inspiring researchers in search of medical breakthroughs — and fueling a dangerous trend in recreational use

Can playing video games make you smarter?

OPINION: Research highlights six key principles for better learning

How the brain calculates a quick escape

Whether fly or human, fleeing from danger is key to staying alive. Scientists are beginning to unravel the complex circuitry behind the split-second decision to beat a hasty retreat.

Color is in the eye, and brain, of the beholder

The way we see and describe hues varies widely for many reasons: from our individual eye structure, to how our brain processes images, to what language we speak, or even if we live near a body of water 

The vital crosstalk between breath and brain

The rhythm of respiration influences a wide range of behaviors, as well as cognition and emotion. Neuroscientists are piecing together how it all works.

The science of a wandering mind

More than just a distraction, mind-wandering (and its cousin, daydreaming) may help us prepare for the future

Cultural transmission makes animals flexible, but vulnerable

From monkeys washing potatoes to cockatoos raiding trash cans, socially spread behaviors allow creatures to adapt more rapidly to changing environments than conventional evolution would allow. But the traits are also more easily lost.

Inside the brains of aging dogs

In a citizen science project, thousands of pet dogs are helping scientists to understand what happens to memory and cognition in old age

The lasting anguish of moral injury

Psychologists are finding that moral code violations can leave an enduring mark — and may require new types of therapy

How to deal with work stress — and actually recover from burnout

Mindfulness, detachment, selecting off-time activities with care: Here are evidence-based strategies to achieve healthy work-life balance

Inside the adolescent brain

This challenging phase of life may get a bad rap, but it’s also full of opportunity. A developmental neuroscientist shares what she’s learned from studies on young people’s risk-taking behavior, reasoning and more.

Sex, immunity and the brain

Differences between the immune systems of males and females — in particular, ones involving cells called microglia — might help explain why the risk for conditions such as autism and Alzheimer’s varies between the sexes

Covid and the brain: A neurological health crisis

VIDEO: Even a mild SARS-CoV-2 infection can cause inflammation that disrupts neural communication, says Stanford neurologist Michelle Monje. Her concern is that Covid-19 may leave millions dealing with cognitive problems, from a loss of mental sharpness to lapses in memory, that prevent them from returning to their previous level of function.

Does online opioid treatment work?

The Covid-19 pandemic brought a sudden shift to virtual health care. That has increased access — and possibly outcomes, too — for patients with opioid use disorder.

The awake ape: Why people sleep less than their primate relatives

Ancient humans may have evolved to slumber efficiently — and in a crowd

How antidepressants changed ideas about depression

PODCAST: Serendipitous discoveries led to drugs like Prozac and to new insights into the physical basis of this debilitating disorder. But scientists continue to search for deeper understandings and therapies that will bring relief to those who still struggle. (Season 2, Episode 6)

Mapping the brain to understand the mind

New technology is enabling neuroscientists to make increasingly detailed wiring diagrams that could yield new insights into brain function

The pain of prolonged grief disorder

Psychologists are beginning to understand that for some people, intense and sustained feelings of loss are symptoms of a serious condition — one that can last for years and erode wellbeing

Pandemic psychology: Nothing new under the Sun

OPINION: Our behavior during Covid-19 echoes that of individuals, societies and governments during past plagues. We can and should do better.

The science of placebos is fueling quackery

OPINION: The placebo effect is real. So are the ethical conundrums posed by those who would exploit the latest research advances for profit.

Do birds have language? It depends on how you define it.

In the cheeps, trills and tweets of birdsong, scientists find some parallels with human speech

Oxytocin’s effects aren’t just about love

At last, neuroscientists are learning how the hormone shapes social behaviors such as pair-bonding and parental care. It’s more complicated than they thought.

The science of dreams

PODCAST: We have thoughts, visions and feelings while we sleep, experiencing a virtual reality of sorts. But how and why does dreaming happen? Researchers bring us closer to understanding the work our brains do while our bodies rest. (Season 2/Episode 1)

How to short-circuit short-term thinking

OPINION: Human behavior is fueling major social dilemmas — from climate change to the Covid pandemic to the spread of misinformation. But that means it’s also the solution, if only we can harness psychology for the common good.

When siblings become caregivers

Collaboration is vital when caring for an aging parent. Yet there are many stumbling blocks to good teamwork, from unequal division of tasks and differing perceptions of a parent’s needs to old, lingering resentments.

When depression sneaks up on menopause

Fluctuating levels of estrogen during a period known as perimenopause can wreak havoc on the mental health of women in midlife. Diagnosis and treatment have been elusive despite symptoms as serious as suicidal thoughts.

The Knowable Magazine Podcast, season 2: Trailer

The science history series audio returns on February 1. Subscribe today.

Exercise boosts the brain — and mental health

Working out buffs up the body — and perhaps the mind, too. New research is revealing how physical activity can reduce and even ward off depression, anxiety and other psychological ailments.

How learning happens in the brains of sleeping babes

Neuroscientists have long known that shut-eye helps consolidate memories in adults. Napping may play an equally crucial role in infants and young children.

The vicious cycle of food and sleep

OPINION: More than a third of Americans don’t log enough hours in bed, provoking serious impacts on their health. Diet is an important and under-recognized reason.

Searching for a better treatment for eating disorders

Cognitive behavioral therapy is proving to work well, but only for some patients. Scientists are seeking new innovations to help people grappling with the pervasive and often-hidden problems of anorexia, bulimia and binge eating.

Wild robots: Five ways scientists are using robotics to study animal behavior

Biomimetic bots can teach researchers a lot about how creatures interact in the natural world

Spiders are much smarter than you think

Cognition researchers are discovering surprising capabilities among a group of itsy-bitsy arachnids

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